Review



sted microscope platform stedycon  (abberior instruments)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    abberior instruments sted microscope platform stedycon
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Sted Microscope Platform Stedycon, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stedycon+microscope+platform/stedycon+sted+microscope/pmc11678420-76-6-10
    Average 90 stars, based on 1 article reviews
    sted microscope platform stedycon - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells"

    Article Title: Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells

    Journal: International Journal of Molecular Sciences

    doi: 10.3390/ijms252413365

    STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Figure Legend Snippet: STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Techniques Used: Control, Labeling, Concentration Assay, Staining

    Related Articles

    Microscopy:

    Article Title: CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement.
    Article Snippet: Zeiss Elyra S.1 3D-SIM system generally achieves a lateral resolution of 140 nm and an axial resolution of 250 nm.47 Acquired images were processed with structured illumination and further adjusted by channel alignment methods in ZEN 2.3 SP1 software. .. The ROSE-Z was conducted based on a previous described protocol.59 STED images were acquired using a STEDYCON microscope platform (Abberior Instruments, Göttingen, Germany). ..

    Article Title: ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia.
    Article Snippet: .. We thank X. li, c. Zheng, and W. J. Goh for helping us acquiring Sted images with the StedYcOn microscope platform (Abberior instruments). ..

    Article Title: α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization
    Article Snippet: .. Confocal and STED images were acquired using either a TCS SP8 STED 3 X microscopy system with a 100 × 1.4 NA APO oil objective lens and LAS X v.2.0 software (Leica Microsystem), or a STEDYCON microscope platform (Abberior Instruments, Göttingen, Germany). ..

    Software:

    Article Title: α-/γ-Taxilin are required for centriolar subdistal appendage assembly and microtubule organization
    Article Snippet: .. Confocal and STED images were acquired using either a TCS SP8 STED 3 X microscopy system with a 100 × 1.4 NA APO oil objective lens and LAS X v.2.0 software (Leica Microsystem), or a STEDYCON microscope platform (Abberior Instruments, Göttingen, Germany). ..



    Similar Products

    sted microscope platform stedycon  (abberior instruments)
    90
    abberior instruments sted microscope platform stedycon
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Sted Microscope Platform Stedycon, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stedycon+microscope+platform/stedycon+sted+microscope/pmc11678420-76-6-10
    Average 90 stars, based on 1 article reviews
    sted microscope platform stedycon - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    stedycon microscope platform  (abberior instruments)
    90
    abberior instruments stedycon microscope platform
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Stedycon Microscope Platform, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stedycon+microscope+platform/stedycon+microscope+platform/pm39231220-716-18-21
    Average 90 stars, based on 1 article reviews
    stedycon microscope platform - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    stedycon sted microscope platform  (Carl Zeiss)
    90
    Carl Zeiss stedycon sted microscope platform
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Stedycon Sted Microscope Platform, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stedycon+microscope+platform/200m+axiovert+microscope/pm30131441-249-6-12
    Average 90 stars, based on 1 article reviews
    stedycon sted microscope platform - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    stedycon sted microscope platform  (abberior instruments)
    90
    abberior instruments stedycon sted microscope platform
    <t>STED</t> nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).
    Stedycon Sted Microscope Platform, supplied by abberior instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/stedycon+microscope+platform/stedycon+sted+microscope/pm30131441-285-12-4
    Average 90 stars, based on 1 article reviews
    stedycon sted microscope platform - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Journal: International Journal of Molecular Sciences

    Article Title: Imaging-Based Molecular Interaction Between Src and Lamin A/C Mechanosensitive Proteins in the Nucleus of Laminopathic Cells

    doi: 10.3390/ijms252413365

    Figure Lengend Snippet: STED nanoscopy of Src and lamin A/C in nuclei from healthy and laminopathic fibroblasts. ( A ) In the healthy control nuclei, Src labeling (green) was thickened at the nuclear periphery, with a diffuse and dotted distribution in the nuclear matrix, whereas some anomalous aggregates were observed (arrows) in patients’ nuclei. Alterations in the structural organization of the lamin A/C (red) meshworks have been seen in several nuclei of the fibroblasts of patient 1 and patient 2 (arrowheads). Colocalization masks (yellow) showed the co-distribution of Src and lamin A/C at the nuclear rim in all samples and a higher concentration in the nucleoplasm of patients’ cells (high magnification of insets). Bars: 5 µm and 2 µm. ( B ) Mean values of the overlap coefficient quantified in STED images of double-stained fibroblast nuclei. (** p < 0.01; * p < 0.05).

    Article Snippet: STED imaging was performed on a STED microscope platform (STEDYCON, Abberior Instruments GmbH, Göttingen, Germany) equipped with an upright Zeiss Axioimager Z.2 microscope (Zeiss Microscopy GmbH, Oberkochen, Germany) and a pulsed STED laser (Abberior Instruments GmbH) with a depletion wavelength of 775 nm working at a repetition rate of 40 MHz, a pulse duration of 1 ns, using STEDYCON SmartControl software version 9.

    Techniques: Control, Labeling, Concentration Assay, Staining